1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one,dodecahydro-, (7aR,13aR,13bR,13cS)-
- 中文别名：槐定碱
- 中文释义：槐定碱;槐定碱(标准品)
- 英文别名：Sophoridine;
Dihydro-5-episophocarpine;
matridin-15-one;
Bio-0637;
5-Epidihydrosophocarpine
- CAS No.：6882-68-4
- 分子式：
C15H24N2O
- 分子量：248.36400
- 精确分子量：248.18900
- PSA：23.55000
- InChI：The Key: ZSBXGIUJOOQZMP-UKTARXLSSA-N
- 分子结构式：
物化性质
- 密度：
- 1.16 g/cm3
- 沸点：
- 396.7ºC at 760 mmHg
- 闪点：
- 172.7ºC
安全信息
- 密度：
- 1.16 g/cm3
- 沸点：
- 396.7ºC at 760 mmHg
- 闪点：
- 172.7ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WG1250000
- CHEMICAL NAME :
- Sophoridine
- CAS REGISTRY NUMBER :
- 6882-68-4
- LAST UPDATED :
- 199412
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C15-H24-N2-O
- MOLECULAR WEIGHT :
- 248.41
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 243 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 27,201,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 64300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 8,153,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YFZADL Yaowu Fenxi Zazhi. Journal of Pharmaceutical Analysis. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1981- Volume(issue)/page/year: 6,96,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 350 mg/kg/35D-I
- TOXIC EFFECTS :
- Blood - changes in leukocyte (WBC) count
- REFERENCE :
- CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 8,153,1987
