1H-Pyrazole-3-ethanamine,hydrochloride (1:2)
- 中文别名：盐酸倍他唑
- 中文释义：盐酸倍他唑
- 英文别名：betazole dihydrochloride;
2-(1(2)H-pyrazol-3-yl)-ethylamine,dihydrochloride;
1h-pyrazole-3-ethanamine,dihydrochloride;
BETAZOLE HYDROCHLORIDE (200 MG);
ametazoledihydrochloride;
Histimin;
gastramine;
2-(1(2)H-Pyrazol-3-yl)-aethylamin,Dihydrochlorid;
histalog;
Betazole hydrochloride;
3-(2-aminoethyl)-pyrazoldihydrochloride;
3-(2-aminoethyl)pyrazole,dihydrochloride;
[2-(1H-Pyrazol-3-yl)ethyl]amine dihydrochloride
- CAS No.：138-92-1
- 分子式：
C5H9N3.2ClH
- 分子量：184.07
- 精确分子量：183.03300
- PSA：54.70000
- InChI：The Key: HLJRAERMLKNULP-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 沸点：
- 284.1ºC at 760mmHg
- 闪点：
- 150.3ºC
- 蒸汽压：
- 0.00303mmHg at 25°C
安全信息
- 沸点：
- 284.1ºC at 760mmHg
- 闪点：
- 150.3ºC
- 蒸汽压：
- 0.00303mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ5600000
- CHEMICAL NAME :
- Pyrazole, 3-(2-aminoethyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 138-92-1
- LAST UPDATED :
- 199404
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C5-H9-N3.2Cl-H
- MOLECULAR WEIGHT :
- 184.09
- WISWESSER LINE NOTATION :
- T5MNJ C2Z &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Ocular
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 740 ug/kg/37D-I
- TOXIC EFFECTS :
- Behavioral - wakefulness Behavioral - somnolence (general depressed activity) Behavioral - anorexia (human)
- REFERENCE :
- AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 102,275,1986
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Ocular
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 86 ug/kg/6D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 102,274,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 860 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 122,685,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 803 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,749,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83995 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 66 (estimated)
海关数据
中国海关编码：2933199090
- 概述：
- 2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
分子结构与计算化学数据
分子结构数据
1、 摩尔折射率：31.86
2、 摩尔体积（cm3/mol）：97.4
3、 等张比容（90.2K）：266.6
4、 表面张力（dyne/cm）：56.0
5、 极化率（10-24cm3）：12.63
