1H-Azepine-4-carboxylicacid, hexahydro-1-methyl-4-phenyl-, ethyl ester
- 中文别名：依索庚嗪
- 中文释义：依索庚嗪
- 英文别名：ethyl 1-methyl-4-phenylazepane-4-carboxylate;
1-Methyl-4-phenyl-hexahydro-azepin-4-carbonsaeure-aethylester;
ETHOHEPTAZINE;
Etoheptazina [INN-Spanish];
Zactane;
Ethoheptazinum [INN-Latin];
(+-)-1-methyl-4-phenyl-hexahydro-azepine-4-carboxylic acid ethyl ester;
Aethoheptazin;
Ethoheptazine [BAN];
Ethyl heptazine
- CAS No.：77-15-6
- 分子式：
C16H23NO2
- 分子量：261.36
- 精确分子量：261.17300
- PSA：29.54000
- InChI：The Key: WGJHHMKQBWSQIY-INIZCTEOSA-N
- 分子结构式：
物化性质
- 密度：
- 1.037 g/cm3
- 沸点：
- 346.4ºC at 760 mmHg
- 闪点：
- 114.4ºC
- 折射率：
- 1.514
安全信息
- 密度：
- 1.037 g/cm3
- 沸点：
- 346.4ºC at 760 mmHg
- 闪点：
- 114.4ºC
- 折射率：
- 1.514
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CM2800000
- CHEMICAL NAME :
- Azepine-4-carboxylic acid, hexahydro-1-methyl-4-phenyl-, ethyl ester
- CAS REGISTRY NUMBER :
- 77-15-6
- BEILSTEIN REFERENCE NO. :
- 0088192
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C16-H23-N-O2
- MOLECULAR WEIGHT :
- 261.40
- WISWESSER LINE NOTATION :
- T7NTJ A1 DVO2 DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 355 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,51,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 34 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,51,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 277 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,51,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 318 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,51,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 65 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 134,154,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 167 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,51,1969
