10H-Phenothiazine,10-[(1-methyl-3-piperidinyl)methyl]-
- 中文别名：哌卡嗪
- 中文释义：哌卡嗪
- 英文别名：10-[(1-methylpiperidin-3-yl)methyl]phenothiazine;
Lacumin;
10-[(1-methyl-3-piperidinyl)methyl]-10H-phenothiazine;
Pecazine;
MEPAZINE;
10-(1-methyl-piperidin-3-ylmethyl)-10H-phenothiazine;
mepasin;
Pacatal;
Nothiazine;
Meprazine;
Mepazin;
Pecatal;
Pakatal;
10-(1-methyl-[3]piperidylmethyl)-phenothiazine
- CAS No.：60-89-9
- 分子式：
C19H22N2S
- 分子量：310.46
- 精确分子量：310.15000
- PSA：31.78000
- InChI：The Key: CBHCDHNUZWWAPP-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.159 g/cm3
- 沸点：
- 444.4ºC at 760 mmHg
- 闪点：
- 222.6ºC
- 折射率：
- 1.627
安全信息
- 密度：
- 1.159 g/cm3
- 沸点：
- 444.4ºC at 760 mmHg
- 闪点：
- 222.6ºC
- 折射率：
- 1.627
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SP2625000
- CHEMICAL NAME :
- Phenothiazine, 10-((1-methyl-3-piperidyl)methyl)-
- CAS REGISTRY NUMBER :
- 60-89-9
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C19-H22-N2-S
- MOLECULAR WEIGHT :
- 310.49
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B1- CT6NTJ A1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,136,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,489,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CANJAE Canadian Anaesthetists' Society Journal. (Toronto, Ont., Canada) V.1-33, 1954-86. Volume(issue)/page/year: 3,224,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,232,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CANJAE Canadian Anaesthetists' Society Journal. (Toronto, Ont., Canada) V.1-33, 1954-86. Volume(issue)/page/year: 3,224,1956 *** REVIEWS *** TOXICOLOGY REVIEW JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For publisher information, see BJPYAJ. Volume(issue)/page/year: 106,755,1960
海关数据
中国海关编码：2934300000
- 概述：
- 2934300000. 含一个吩噻嗪环系的化合物(吩噻嗪环系不论是否氢化,化合物未经进一步稠合的 ). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
