4α,9-Epoxy-5β-cevan-3α,4β,12,14,16β,17,20-heptaol
- 中文别名：4a,9-环氧瑟烷-3b,4,7a,14,15a,16b,20-七醇
- 英文别名：4α,9-Epoxy-5β-cevan-3α,4β,12,14,16β,17,20-heptaol;
cevine;
SABADININE
- CAS No.：508-65-6
- 分子式：C27H43NO8
- 分子量：509.63200
- 精确分子量：509.29900
- PSA：154.08000
- InChI：The Key: RNPABQVCNAUEIY-GUQYYFCISA-N
- 分子结构式：
物化性质
- 密度：
- 1.49g/cm3
- 沸点：
- 688.2ºC at 760 mmHg
- 闪点：
- 370ºC
- 折射率：
- 1.679
安全信息
- 密度：
- 1.49g/cm3
- 沸点：
- 688.2ºC at 760 mmHg
- 闪点：
- 370ºC
- 折射率：
- 1.679
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FL4725000
- CHEMICAL NAME :
- Cevane-3-beta,4-beta,7-alpha,14,15-alpha,16-beta,20-h eptol, 4,9-epoxy-
- CAS REGISTRY NUMBER :
- 508-65-6
- BEILSTEIN REFERENCE NO. :
- 0099115
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C27-H43-N-O8
- MOLECULAR WEIGHT :
- 509.71
- WISWESSER LINE NOTATION :
- T J6 H6 E6 D5665/TC& 3ATU C& ON TX C&OTJ CQ EQ FQ GQ IQ I1 M1 U1 A&Q B&Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 189,397,1938
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 113,89,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 189,397,1938 *** REVIEWS *** TOXICOLOGY REVIEW LYPHAD Lyon Pharmaceutique. (Medipharly, 12, rue de la Barre, 69002 Lyons, France) V.1- 1950- Volume(issue)/page/year: 26,5,1975
