2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
- 中文别名：2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
- 中文释义：2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
- 英文别名：2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;
6-Methyl-2-phthalimido-glutarimid;
methyl-thalidomide;
Glutarimide,N-methyl-2-phthalimido;
N-methyl thalidomide;
2-Phthalimido-N-methyl-glutarimide;
2-(1-methyl-2,6-dioxopiperidin-3-yl)-1h-isoindole-1,3(2h)-dione;
N-Methyl-2-phthalimidoglutarimide
- CAS No.：42472-93-5
- 分子式：C14H12N2O4
- 分子量：272.25600
- 精确分子量：272.08000
- PSA：74.76000
- InChI：The Key: IYYPLFUVXTVBLD-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.457g/cm3
- 沸点：
- 477ºC at 760 mmHg
- 闪点：
- 232ºC
- 折射率：
- 1.64
安全信息
- 密度：
- 1.457g/cm3
- 沸点：
- 477ºC at 760 mmHg
- 闪点：
- 232ºC
- 折射率：
- 1.64
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA5300000
- CHEMICAL NAME :
- Glutarimide, N-methyl-2-phthalimido-
- CAS REGISTRY NUMBER :
- 42472-93-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C14-H12-N2-O4
- MOLECULAR WEIGHT :
- 272.28
- WISWESSER LINE NOTATION :
- T56 BVNVJ C- DT6VNVTJ B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 670 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 3,721,1964 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 650 mg/kg
- SEX/DURATION :
- female 4-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - body wall Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 3,721,1964
