1,3,4,7,8,9,10,10-Octachlorotricyclo[5.2.1.0<sup>2,6</sup>]dec-8-ene
- 中文别名：氯丹（技术混合物）
- 中文释义：氯丹（技术混合物）;氯丹
- 英文别名：1,3,4,7,8,9,10,10-Octachlorotricyclo[5.2.1.02,6]dec-8-ene;
1,2,4,5,6,7,8,9-octachloro-3a,4,7,7a-tetrahydro-7-methanoinden;
chlordane(technicalmixtureandmetabolites);
chlordane,technical;
CHLORDAN TECHNICAL MIXTURE PESTANAL;
CHLORDAN TECHNICAL MIXTURE, PESTANAL, 25;
chlordane (technical mixture);
TECHNICALCHLORDANE;
Silica Gel, For Chromatography, Ultrapure
- CAS No.：12789-03-6
- 分子式：
C10H6Cl8
- 分子量：409.77900
- 精确分子量：405.79800
- PSA：0.00000
- 分子结构式：
物化性质
- 密度：
- 1.8g/cm3
- 熔点：
- 106-107ºC
- 沸点：
- 424.7ºC at 760mmHg
- 闪点：
- 212.5ºC
- 折射率：
- 1.627
- 蒸汽压：
- 5.02E-07mmHg at 25°C
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开储运
安全信息
- 密度：
- 1.8g/cm3
- 熔点：
- 106-107ºC
- 沸点：
- 424.7ºC at 760mmHg
- 闪点：
- 212.5ºC
- 折射率：
- 1.627
- 蒸汽压：
- 5.02E-07mmHg at 25°C
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开储运
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FN5955000
- CHEMICAL NAME :
- Chlordane
- CAS REGISTRY NUMBER :
- 12789-03-6
- LAST UPDATED :
- 199609
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 283 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg/28D-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 880 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 144 mg/kg
- SEX/DURATION :
- female 1-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - biochemical and metabolic
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 1,241,1980 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 51590 No. of Facilities: 1431 (estimated) No. of Industries: 17 No. of Occupations: 19 No. of Employees: 20937 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 51590 No. of Facilities: 387 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 3833 (estimated) No. of Female Employees: 574 (estimated)
