1-Propanamine,3,3'-[1,2-ethanediylbis(oxy)]bis-
- 中文别名：乙二醇二(3-氨丙基)醚
- 中文释义：乙二醇双(3-胺丙基)醚;乙二醇二(3-氨丙基)醚;乙二醇双（3-氨丙基）醚;3,3-(乙烷-1,2-二yl双(氧基))双(丙烷-1-胺)
- 英文别名：3-[2-(3-aminopropoxy)ethoxy]propan-1-amine;
Jeffamine 176;
1,2-Bis(3-aminopropoxy)ethane;
3,3'-(Ethane-1,2-diylbis(oxy))bis(propan-1-amine);
EINECS 221-067-4;
1,10-Diamino-4,7-dioxadecane;
4,7-Dioxadecane-1,10-diamine;
Ethylene Glycol Bis(3-aMinopropyl) Ether
- CAS No.：2997-01-5
- 分子式：
C8H20N2O2
- 分子量：176.26
- 精确分子量：176.15200
- PSA：70.50000
- InChI：InChI=1/C8H20N2O2/c9-3-1-5-11-7-8-12-6-2-4-10/h1-10H2/p+2
- 分子结构式：
物化性质
- 密度：
- 0.975g/cm3
- 沸点：
- 275.9ºC at 760mmHg
- 闪点：
- 121.5ºC
- 蒸汽压：
- 0.00495mmHg at 25°C
- 存储条件/存储方法：
密闭于阴凉干燥环境中
- 稳定性相关：
遵照规定使用和储存则不会分解。
- 其它信息：
1. 性状：无可用
2. 密度（g/mL,25/4℃）：0.9837
3. 相对蒸汽密度（g/mL,空气=1）：无可用
4. 熔点（ºC）：无可用
5. 沸点（ºC,常压）：127-130
6. 沸点（ºC,5.2kPa）：无可用
7. 折射率：无可用
8. 闪点（ºC）：无可用
9. 比旋光度（º）：无可用
10. 自燃点或引燃温度（ºC）：无可用
11. 蒸气压（kPa,25ºC）：无可用
12. 饱和蒸气压（kPa,60ºC）：无可用
13. 燃烧热（KJ/mol）：无可用
14. 临界温度（ºC）：无可用
15. 临界压力（KPa）：无可用
16. 油水（辛醇/水）分配系数的对数值：无可用
17. 爆炸上限（%,V/V）：无可用
18. 爆炸下限（%,V/V）：无可用
19. 溶解性：无可用
安全信息
- 密度：
- 0.975g/cm3
- 沸点：
- 275.9ºC at 760mmHg
- 闪点：
- 121.5ºC
- 蒸汽压：
- 0.00495mmHg at 25°C
- 存储条件/存储方法：
密闭于阴凉干燥环境中
- 稳定性相关：
遵照规定使用和储存则不会分解。
- 其它信息：
1. 性状：无可用
2. 密度（g/mL,25/4℃）：0.9837
3. 相对蒸汽密度（g/mL,空气=1）：无可用
4. 熔点（ºC）：无可用
5. 沸点（ºC,常压）：127-130
6. 沸点（ºC,5.2kPa）：无可用
7. 折射率：无可用
8. 闪点（ºC）：无可用
9. 比旋光度（º）：无可用
10. 自燃点或引燃温度（ºC）：无可用
11. 蒸气压（kPa,25ºC）：无可用
12. 饱和蒸气压（kPa,60ºC）：无可用
13. 燃烧热（KJ/mol）：无可用
14. 临界温度（ºC）：无可用
15. 临界压力（KPa）：无可用
16. 油水（辛醇/水）分配系数的对数值：无可用
17. 爆炸上限（%,V/V）：无可用
18. 爆炸下限（%,V/V）：无可用
19. 溶解性：无可用
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UI2800000
- CHEMICAL NAME :
- Propylamine, 3,3'-(ethylenedioxy)bis-
- CAS REGISTRY NUMBER :
- 2997-01-5
- BEILSTEIN REFERENCE NO. :
- 1744355
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C8-H20-N2-O2
- MOLECULAR WEIGHT :
- 176.30
- WISWESSER LINE NOTATION :
- Z3O2O3Z
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2830 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1250 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
- 生态数据：
该物质对环境可能有危害，对水体应给予特别注意。
MSDS
| Name: | 1 10-Diamino-4 7-dioxadecane Material Safety Data Sheet |
| Synonym: | |
| CAS: | 2997-01-5 |
Section 1 - Chemical Product MSDS Name:1 10-Diamino-4 7-dioxadecane Material Safety Data Sheet
Synonym:
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | content | EINECS# |
| 2997-01-5 | 1,10-Diamino-4,7-dioxadecane | | 221-067-4 |
Hazard Symbols: C
Risk Phrases: 21 34
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful in contact with skin. Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Harmful if absorbed through the skin. Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Section 7 - HANDLING and STORAGE
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 2997-01-5: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 127 - 130 deg C @7mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 0.984
Molecular Formula: C8H20N2O2
Molecular Weight: 176.26
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 2997-01-5: UI2800000 LD50/LC50:
CAS# 2997-01-5: Oral, rat: LD50 = 2830 uL/kg; Skin, rabbit: LD50 = 1250 uL/kg.
Carcinogenicity:
1,10-Diamino-4,7-dioxadecane - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S.*
Hazard Class: 8
UN Number: 2735
Packing Group: III
IMO
Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 2735
Packing Group: III
RID/ADR
Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 2735
Packing group: III
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 21 Harmful in contact with skin.
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 2997-01-5: No information available.
Canada
CAS# 2997-01-5 is listed on Canada's NDSL List.
CAS# 2997-01-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 2997-01-5 is listed on the TSCA inventory.
SECTION 16 - ADDITIONAL INFORMATION
N/A
海关数据
中国海关编码：2922199090
- 概述：
- 2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
- 摘要/Summary：
- 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
分子结构与计算化学数据
分子结构数据
1、 摩尔折射率：49.67
2、 摩尔体积（m3/mol）：180.6
3、 等张比容（90.2K）：447.8
4、 表面张力（dyne/cm）：37.7
5、 极化率（10-24cm3）：19.69
计算化学数据
1、 疏水参数计算参考值（XlogP）：-1.2
2、 氢键供体数量：2
3、 氢键受体数量：2
4、 可旋转化学键数量：9
5、 拓扑分子极性表面积（TPSA）：73.7
6、 重原子数量：12
7、 表面电荷：0
8、 复杂度：71.5
9、 同位素原子数量：0
10、 确定原子立构中心数量：0
11、 不确定原子立构中心数量：0
12、 确定化学键立构中心数量：0
13、 不确定化学键立构中心数量：0
14、 共价键单元数量：1
