laurolistine
- 中文别名：去甲异波尔定
- 中文释义：新木姜子碱;去甲异波尔定;(S)-5,6,6A,7-四氢-1,10-二甲氧基-4H-二苯并[DE,G]喹啉-2,9-二醇
- 英文别名：laurolistine;
Laurolistine;
Norisoboidine;
LAUROLITSINE;
Norboldine
- CAS No.：5890-18-6
- 分子式：
C18H19NO4
- 分子量：313.34800
- 精确分子量：313.13100
- PSA：70.95000
- InChI：The Key: KYVJVURXKAZJRK-LBPRGKRZSA-N
- 分子结构式：
物化性质
- 密度：
- 1.313
- 熔点：
- 138-140ºC
- 沸点：
- 553ºC at 760mmHg
- 闪点：
- 288.3ºC
安全信息
- 密度：
- 1.313
- 熔点：
- 138-140ºC
- 沸点：
- 553ºC at 760mmHg
- 闪点：
- 288.3ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RB5935000
- CHEMICAL NAME :
- 6a-alpha-Noraporphine-2,9-diol, 1,10-dimethoxy-
- CAS REGISTRY NUMBER :
- 5890-18-6
- LAST UPDATED :
- 198208
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C18-H19-N-O4
- MOLECULAR WEIGHT :
- 313.38
- WISWESSER LINE NOTATION :
- T C6666 1A Q KM&TT&J EO1 FQ PQ QO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 170 mg/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 38,537,1980
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