9H-Fluoren-9-one,2,7-bis[2-(diethylamino)ethoxy]-
- 中文别名：替洛隆; 梯洛龙; 2,7-双[2-(二乙基氨基)乙氧基]-9-芴酮
- 中文释义：乙胺芴酮;泰洛伦;2,7-双[2-(二乙基氨基)乙氧基]-9-芴酮
- 英文别名：2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one;
tilorone;
Bis-DEAE-fluorenone;
Tilorone base;
Tilorone hydrochloride
- CAS No.：27591-97-5
- 分子式：C25H34N2O3
- 分子量：410.55
- 精确分子量：410.25700
- PSA：42.01000
- InChI：InChI=1/C25H34N2O3/c1-5-26(6-2)13-15-29-19-9-11-21-22-12-10-20(30-16-14-27(7-3)8-4)18-24(22)25(28)23(21)17-19/h9-12,17-18H,5-8,13-16H2,1-4H3
- 分子结构式：
物化性质
- 密度：
- 1.102g/cm3
- 沸点：
- 552.3ºC at 760mmHg
- 闪点：
- 287.8ºC
- 折射率：
- 1.563
- 蒸汽压：
- 3.05E-12mmHg at 25°C
安全信息
- 密度：
- 1.102g/cm3
- 沸点：
- 552.3ºC at 760mmHg
- 闪点：
- 287.8ºC
- 折射率：
- 1.563
- 蒸汽压：
- 3.05E-12mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LL8990000
- CHEMICAL NAME :
- 9H-Fluoren-9-one, 2,7-bis(2-(diethylamino)ethoxy)-
- CAS REGISTRY NUMBER :
- 27591-97-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C25-H34-N2-O3
- MOLECULAR WEIGHT :
- 410.61
- WISWESSER LINE NOTATION :
- L B656 HVJ EO2N2&2 KO2N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1780 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 121 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Immunological Including Allergic - increased immune response Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 11,91,1975
