19-Norpregna-4,9,11-trien-20-yn-3-one,17-hydroxy-, (17a)-
- 中文别名：诺孕烯酮; 三烯炔诺酮
- 中文释义：诺孕烯酮;三烯炔诺酮
- 英文别名：17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one;
Ethynyl trienolone;
Ogyline
- CAS No.：848-21-5
- 分子式：
C20H22O2
- 分子量：294.39
- 精确分子量：294.16200
- PSA：37.30000
- InChI：The Key: GVDMJXQHPUYPHP-GUMHCPJTSA-N
- 分子结构式：
物化性质
- 密度：
- 1.21g/cm3
- 熔点：
- 169ºC
- 沸点：
- 498.1ºC at 760 mmHg
- 闪点：
- 211.2ºC
- 折射率：
- 1.615
安全信息
- 密度：
- 1.21g/cm3
- 熔点：
- 169ºC
- 沸点：
- 498.1ºC at 760 mmHg
- 闪点：
- 211.2ºC
- 折射率：
- 1.615
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RC8960080
- CHEMICAL NAME :
- 19-Nor-17-alpha-pregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-
- CAS REGISTRY NUMBER :
- 848-21-5
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H22-O2
- MOLECULAR WEIGHT :
- 294.42
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 1168 ug/kg
- SEX/DURATION :
- female 52 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,411,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 1642 ug/kg
- SEX/DURATION :
- female 52 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,429,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 1 mg/kg
- SEX/DURATION :
- female 36 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 20,511,1979
