10H-Phenothiazine-10-ethanamine,N,N-dimethyl-
- 中文别名：芬乙嗪
- 中文释义：芬乙嗪
- 英文别名：N,N-dimethyl-2-phenothiazin-10-ylethanamine;
Anergen;
Ethysene;
Phenetazine;
Phenethazinum;
Ethysine;
Ethyzine;
Fenethazine;
Anergell;
Phenethazine;
Ethizine
- CAS No.：522-24-7
- 分子式：
C16H18N2S
- 分子量：0
- 精确分子量：270.11900
- PSA：31.78000
- InChI：The Key: PFAXACNYGZVKMX-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.153g/cm3
- 沸点：
- 396.1ºC at 760mmHg
- 闪点：
- 193.3ºC
- 折射率：
- 1.628
安全信息
- 密度：
- 1.153g/cm3
- 沸点：
- 396.1ºC at 760mmHg
- 闪点：
- 193.3ºC
- 折射率：
- 1.628
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO5250000
- CHEMICAL NAME :
- Phenothiazine, 10-(2-(dimethylamino)ethyl)-
- CAS REGISTRY NUMBER :
- 522-24-7
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H18-N2-S
- MOLECULAR WEIGHT :
- 270.42
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B2N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 364 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,489,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,171,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 190 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 31,53,1968
海关数据
中国海关编码：2934300000
- 概述：
- 2934300000. 含一个吩噻嗪环系的化合物(吩噻嗪环系不论是否氢化,化合物未经进一步稠合的 ). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
分子结构与计算化学数据
计算化学数据
1.疏水参数计算参考值（XlogP）:无
2.氢键供体数量:0
3.氢键受体数量:3
4.可旋转化学键数量:3
5.互变异构体数量:无
6.拓扑分子极性表面积:31.8
7.重原子数量:19
8.表面电荷:0
9.复杂度:273
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1
