10H-Phenothiazine-10-propanamine,2-methoxy-N,N,b-trimethyl-,hydrochloride (1:1), (bR)-
- 中文别名：左美丙嗪盐酸盐; 10-(3-二甲基氨基-2-甲基丙基)-2-甲氧基吩噻嗪盐酸盐
- 中文释义：左美丙嗪盐酸盐;10-(3-二甲基氨基-2-甲基丙基)-2-甲氧基吩噻嗪盐酸盐
- 英文别名：Levomepromazine hydrochloride;
methotrimeprazine hydrochloride;
Levopromazine hydrochloride;
Einecs 214-978-3;
(R)-3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropylamine hydrochloride;
Levomepromazinium chloride;
7044 Rp hydrochloride;
LevomepromazineHCl
- CAS No.：1236-99-3
- 分子式：
C19H24N2OS.ClH
- 分子量：364.93
- 精确分子量：364.13800
- PSA：41.01000
- InChI：The Key: ODLGFPIWRAEFAN-PFEQFJNWSA-N
- 分子结构式：
物化性质
- 沸点：
- 468ºC at 760 mmHg
- 闪点：
- 236.8ºC
- 蒸汽压：
- 6.22E-09mmHg at 25°C
安全信息
- 沸点：
- 468ºC at 760 mmHg
- 闪点：
- 236.8ºC
- 蒸汽压：
- 6.22E-09mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO6150000
- CHEMICAL NAME :
- Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-methoxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 1236-99-3
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H24-N2-O-S.Cl-H
- MOLECULAR WEIGHT :
- 364.97
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B1Y1&1N1&1 EO1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 15,455,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 135 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 160,1852,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 360 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 155,1029,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Behavioral - sleep
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 19,87,1962
