1-Piperazineethanol,4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-, hydrochloride (1:2)
- 中文别名：4-[3-(10H-吡啶并[3,2-b][1,4]苯并噻嗪-10-基)丙基]哌嗪-1-乙醇二盐酸
- 中文释义：4-[3-(10H-吡啶并[3,2-b][1,4]苯并噻嗪-10-基)丙基]哌嗪-1-乙醇二盐酸
- 英文别名：Oxypendyl dihydrochloride;
perthipendyl,dihydrochloride;
2-[4-(3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-piperazin-1-yl]-ethanol,dihydrochloride;
Pervetral;
4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]piperazine-1-ethanol dihydrochloride;
1-Piperazineethanol,4-[3-(10H-pyrido[3,2-B][1,4]benzothiazin-10-yl)propyl]-,dihydrochloride;
oxypendyl,dihydrochloride;
Pervetral dihydrochloride
- CAS No.：17297-82-4
- 分子式：
C20H26N4OS.2ClH
- 分子量：443.48
- 精确分子量：406.15900
- PSA：68.14000
- InChI：The Key: VGYCFAGKTGBWJD-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.22g/cm3
- 沸点：
- 575.5ºC at 760mmHg
- 闪点：
- 301.8ºC
- 蒸汽压：
- 4.39E-14mmHg at 25°C
安全信息
- 密度：
- 1.22g/cm3
- 沸点：
- 575.5ºC at 760mmHg
- 闪点：
- 301.8ºC
- 蒸汽压：
- 4.39E-14mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL9450000
- CHEMICAL NAME :
- 1-Piperazineethanol, 4-(3-(10H-pyrido(3,2-b)(1,4)benzothiazin-10-yl)propyl )-, dihydrochloride
- CAS REGISTRY NUMBER :
- 17297-82-4
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C20-H26-N4-O-S.2Cl-H
- MOLECULAR WEIGHT :
- 443.48
- WISWESSER LINE NOTATION :
- T C666 BS DN INJ I3- AT6N DNTJ D2Q &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1610 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 735 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 139 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,435,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 352 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972
