19-Norpregna-4,20-dien-3-one,17-hydroxy-, (17a)-
- 中文别名：诺乙烯酮
- 中文释义：诺乙烯酮
- 英文别名：(8R,9S,10R,13S,14S,17R)-17-ethenyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one;
Nor-progestelea;
17-Vinyl-19-nortestosterone;
Norvinisterone;
Norvinisterona [INN-Spanish];
SC 4641;
Norvinisteronum [INN-Latin];
Neoprogestin
- CAS No.：6795-60-4
- 分子式：
C20H28O2
- 分子量：300.48
- 精确分子量：300.20900
- PSA：37.30000
- InChI：The Key: VOJYZDFYEHKHAP-RZXUBOOQSA-N
- 分子结构式：
物化性质
- 密度：
- 1.11g/cm3
- 沸点：
- 444ºC at 760 mmHg
- 闪点：
- 189.2ºC
- 折射率：
- 1.565
安全信息
- 密度：
- 1.11g/cm3
- 沸点：
- 444ºC at 760 mmHg
- 闪点：
- 189.2ºC
- 折射率：
- 1.565
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RC8899550
- CHEMICAL NAME :
- 19-Nor-17-alpha-pregna-4,20-dien-3-one, 17-hydroxy-
- CAS REGISTRY NUMBER :
- 6795-60-4
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H28-O2
- MOLECULAR WEIGHT :
- 300.48
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 28 mg/kg
- SEX/DURATION :
- male 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 71,500,1958
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 112 mg/kg
- SEX/DURATION :
- male 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 71,500,1958
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 8 mg/kg
- SEX/DURATION :
- male 3 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,29,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 500 ug/kg
- SEX/DURATION :
- female 5 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 142,469,1962
