1,2-Propanediamine,N1,N1-dimethyl-N2-(1-nitro-9-acridinyl)-, hydrochloride (1:2)
- 中文别名：1-硝基-9-((2-二甲基氨基)-1-甲基乙基氨基)-吖啶二盐酸盐
- 英文别名：C 829
- CAS No.：65094-73-7
- 分子式：
C18H20N4O2.2ClH
- 分子量：397.34
- 精确分子量：360.13500
- PSA：73.98000
- 分子结构式：
物化性质
- 密度：
- 1.267g/cm3
- 沸点：
- 512.7ºC at 760 mmHg
- 闪点：
- 263.9ºC
- 折射率：
- 1.695
安全信息
- 密度：
- 1.267g/cm3
- 沸点：
- 512.7ºC at 760 mmHg
- 闪点：
- 263.9ºC
- 折射率：
- 1.695
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX7955000
- CHEMICAL NAME :
- 1,2-Propanediamine, N(sup 1),N(sup 1)-dimethyl-N(sup 2)-(1-nitro-9-acridinyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 65094-73-7
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C18-H20-N4-O2.2Cl-H
- MOLECULAR WEIGHT :
- 397.34
- WISWESSER LINE NOTATION :
- T C666 BNJ GNW IMY1&1N1&1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 105 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - decreased motility or constipation Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 99200 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - decreased motility or constipation Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 80 nmol/L/69H
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,93,1979
