4-Quinolinemethanol, a-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-,(aS)-rel-
- 中文别名：甲氟喹
- 中文释义：甲氟喹;氟甲喹羟哌啶
- 英文别名：MEFLOQUINE;
Pachycarpidine;
OXYMATRINE;
Kurainone;
matrine,1-oxide;
matrine n-oxide;
Oxymatrine std.
- CAS No.：53230-10-7
- 分子式：C17H16F6N2O
- 分子量：378.31
- 精确分子量：378.11700
- PSA：45.15000
- InChI：The Key: XEEQGYMUWCZPDN-SWLSCSKDSA-N
- 分子结构式：
物化性质
- 密度：
- 1.383g/cm3
- 熔点：
- 242-244ºC
- 沸点：
- 415.7ºC at 760mmHg
- 闪点：
- 205.2ºC
- 折射率：
- 1.519
安全信息
- 密度：
- 1.383g/cm3
- 熔点：
- 242-244ºC
- 沸点：
- 415.7ºC at 760mmHg
- 闪点：
- 205.2ºC
- 折射率：
- 1.519
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VC0333400
- CHEMICAL NAME :
- 4-Quinolinemethanol, alpha-2-piperidinyl-2,8-bis(trifluoromethyl)-, (R*,S*)-(+-)-
- CAS REGISTRY NUMBER :
- 53230-10-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H16-F6-N2-O
- MOLECULAR WEIGHT :
- 378.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 25 mg/kg/5W-I
- TOXIC EFFECTS :
- Behavioral - muscle weakness Musculoskeletal - joints Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 123,894,1995
