18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione,4-[(O-2,6-dideoxy-a-L-ribo-hexopyranosyl-(1®3)-O-[2,6-dideoxy-4-O-methyl-b-L-ribo-hexopyranosyl-(1®4)]-O-2,6-dideoxy-a-L-ribo-hexopyranosyl-(1®3)-2,6-d
- 中文别名：基雅尼霉素
- 中文释义：From Actinomadura Kijaniata
- 英文别名：From Actinomadura Kijaniata;
kijanimicin
- CAS No.：78798-08-0
- 分子式：
C67H100N2O24
- 分子量：0
- 精确分子量：1316.67000
- PSA：350.43000
- InChI：The Key: AAHYWTFSLXCSNH-DYYADRANSA-N
- 分子结构式：
物化性质
- 密度：
- 1.35g/cm3
- 折射率：
- 1.596
安全信息
- 密度：
- 1.35g/cm3
- 折射率：
- 1.596
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OB8650500
- CHEMICAL NAME :
- Kijanimicin
- CAS REGISTRY NUMBER :
- 78798-08-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C67-H100-N2-O24
- MOLECULAR WEIGHT :
- 1317.69
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - peritonitis
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,6,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #33840
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 170 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - peritonitis
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,6,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #33840
