4-Hexenoic acid,6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-,sodium salt (1:1), (4E)-
- 中文别名：霉酚酸钠
- 中文释义：霉酚酸钠;吗替麦考酚钠
- 英文别名：mycophenolate sodium;
mycophenolicmonosodiumsalt;
MYCOPHENOLATE SODIUM;
Mycophenolic acid monosodium salt;
sodiummycophenolate;
mycophenolicacidmonosodiumsalt
- CAS No.：37415-62-6
- 分子式：C17H20O6.Na
- 分子量：342.35
- 精确分子量：343.11600
- PSA：93.06000
- 分子结构式：
物化性质
- 密度：
- 1.29 g/cm3
- 沸点：
- 611.6ºC at 760 mmHg
- 闪点：
- 225.8ºC
安全信息
- 密度：
- 1.29 g/cm3
- 沸点：
- 611.6ºC at 760 mmHg
- 闪点：
- 225.8ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MP8100000
- CHEMICAL NAME :
- 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4 -methyl-, sodium salt
- CAS REGISTRY NUMBER :
- 37415-62-6
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C17-H19-O6.Na
- MOLECULAR WEIGHT :
- 342.35
- WISWESSER LINE NOTATION :
- T56 BVO DHJ FQ G2UY1&2VO HO1 I1 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1176 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 568 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Fibroblast
- DOSE/DURATION :
- 100 ug/L
- REFERENCE :
- BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 113,515,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83943 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 99 (estimated)
