1H-1,4-Diazepine-1-ethanol,hexahydro-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-,hydrochloride (1:2)
- 中文别名：六氢-4-[3-[2-(三氟甲基)-10H-吩噻嗪-10-基]丙基]-1H-1,4-二氮杂卓-1-乙醇二盐酸盐
- 中文释义：1H-1,4-Diazepine-1-ethanol,hexahydro-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-,hydrochloride (1:2)
- 英文别名：1H-1,4-Diazepine-1-ethanol,hexahydro-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-,hydrochloride (1:2);
Homofenazin dihydrochloride;
Homophenazine;
Oldagen;
Homofenazine dihydrochloride;
Homophenazine dihydrochloride;
Homofenazin-dihydrochlorid
- CAS No.：1256-01-5
- 分子式：
C23H28F3N3OS.2ClH
- 分子量：524.4700096
- 精确分子量：487.16700
- PSA：55.25000
- InChI：The Key: JQOGQVPDLQTZQC-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 沸点：
- 574ºC at 760 mmHg
- 闪点：
- 301ºC
- 蒸汽压：
- 5.12E-14mmHg at 25°C
安全信息
- 沸点：
- 574ºC at 760 mmHg
- 闪点：
- 301ºC
- 蒸汽压：
- 5.12E-14mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HM4025000
- CHEMICAL NAME :
- 1H-1,4-Diazepine, hexahydro-1-(2-hydroxyethyl)-4-(3-((2-trifluoromethyl phenothiazinyl)- 10)-propyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 1256-01-5
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C23-H28-F3-N3-O-S.2Cl-H
- MOLECULAR WEIGHT :
- 524.52
- WISWESSER LINE NOTATION :
- T C666 BN ISJ FXFFF B3- AT7N DNTJ D2Q &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 880 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 166 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 102 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 138 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 960 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 73500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,25,1972
