1H-Purine-2,6-dione,3,9-dihydro-1,3-dimethyl-, sodium salt (1:1)
- 中文别名：3,7-二氢-1,3-二甲基-1H-嘌呤-2,6-二酮钠盐
- 英文别名：3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, sodium salt;
1H-Purine-2,6-dione,3,7-dihydro-1,3-dimethyl-,sodium salt;
sodium salt of theophylline;
Einecs 222-472-9;
1,3-DIMETHYLXANTHINE SODIUM SALT;
sodium thiophyllinate;
heophylline,sodium deriv.;
6-dione,3,7-dihydro-1,3-dimethyl-1h-purine-sodium salt;
Theophyllinesodiumsalt;
sodium theophylline;
1H-Purine-2,6-dione,3,9-dihydro-1,3-dimethyl-,sodium salt (1:1)
- CAS No.：3485-82-3
- 分子式：
C7H8N4O2.Na
- 分子量：203.18
- 精确分子量：202.04700
- PSA：69.78000
- InChI：The Key: QVGLHVDBDYLFON-UHFFFAOYSA-M
- 分子结构式：
物化性质
- 沸点：
- 271.1ºC at 760mmHg
- 闪点：
- 117.8ºC
安全信息
- 沸点：
- 271.1ºC at 760mmHg
- 闪点：
- 117.8ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XH6700000
- CHEMICAL NAME :
- Theophylline, sodium deriv.
- CAS REGISTRY NUMBER :
- 3485-82-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C7-H8-N4-O2.Na
- MOLECULAR WEIGHT :
- 203.18
- WISWESSER LINE NOTATION :
- T56 BM DN FNVNVJ F1 H1 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 35,266,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 445 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4325956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 189 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,649,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 171 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,335,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 192 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,649,1954
海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
