4(3H)-Pyrimidinone,5-(1,3-benzodioxol-5-ylmethyl)-2-[[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]amino]-
- 中文别名：奥美替丁
- 中文释义：奥美替丁
- 英文别名：oxmetidine;
Oxmetidina;
OXMETIDINE;
EINECS 276-926-6;
Oxmetidine [INN:BAN];
Oxmetidinum [INN-Latin];
Oxmetidinum;
5-(1,3-benzodioxol-5-ylmethyl)-2-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethylamino]-1H-pyrimidin-6-one;
Oxmetidina [INN-Spanish]
- CAS No.：72830-39-8
- 分子式：C19H21N5O3S
- 分子量：0
- 精确分子量：399.13700
- PSA：130.22000
- InChI：The Key: YTBDPHYVGACIPC-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.47g/cm3
- 沸点：
- 667ºC at 760 mmHg
- 闪点：
- 357.2ºC
- 折射率：
- 1.712
安全信息
- 密度：
- 1.47g/cm3
- 沸点：
- 667ºC at 760 mmHg
- 闪点：
- 357.2ºC
- 折射率：
- 1.712
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UW7371000
- CHEMICAL NAME :
- 4(1H)-Pyrimidinone, 5-(1,3-benzodioxol-5-ylmethyl)-2-((2-(((5-methyl-1H-i midazol-4-yl)methyl) thio)ethyl)amino)-
- CAS REGISTRY NUMBER :
- 72830-39-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C19-H21-N5-O3-S
- MOLECULAR WEIGHT :
- 399.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 104 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 24,65,1989
