1,2-Pyrrolidinedicarboxylicacid, 2-(4-nitrophenyl) 1-(phenylmethyl) ester, (2S)-

物化性质

外观与性状：

白色至略黄色结晶粉末

密度：

1.356 g/cm3

沸点：

541.7ºC at 760 mmHg

闪点：

281.4ºC

折射率：

1.611

安全信息

外观与性状：

白色至略黄色结晶粉末

密度：

1.356 g/cm3

沸点：

541.7ºC at 760 mmHg

闪点：

281.4ºC

折射率：

1.611

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UY0750000

CHEMICAL NAME :

1,2-Pyrrolidinedicarboxylic acid, 1-benzyl p-nitrophenyl ester, L-

CAS REGISTRY NUMBER :

3304-59-4

BEILSTEIN REFERENCE NO. :

0056776

LAST UPDATED :

199612

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C19-H18-N2-O6

MOLECULAR WEIGHT :

370.39

WISWESSER LINE NOTATION :

T5KTJ AVO A1R& BVOR DNW -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

320 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02163

MSDS

Version 1.2
Regulation (EC) No 1907/2006
1 - Product and Company Information
Product NameN-CBZ-L-PROLINE P-NITROPHENYL ESTER
CRYSTALLINE
2 - Hazards Identification
3 - Composition/Information on Ingredients
Product NameCAS #EC noAnnex I
Index Number
N-CBZ-L-PROLINE P-NITROPHENYL3304-59-4 221-981-3 None
ESTERCRYSTALLINE
FormulaC19H18N2O6
Molecular Weight 370,4000 AMU
Synonyms1-Benzyl p-nitrophenyl
L-1,2-pyrrolidinedicarboxylate *
Carbobenzyloxy-L-proline p-nitrophenyl ester *
L-Proline, carbobenzyloxy-, p-nitrophenyl ester
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
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conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear protective equipment.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
STORAGE
Store at 2-8°C
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Special Protective Measures: Wear appropriate government approved
respirator, chemical-resistant gloves, safety goggles, other
protective clothing.
9 - Physical and Chemical Properties
AppearancePhysical State: Solid
PropertyValueAt Temperature or Pressure
pHN/A
BP/BP RangeN/A
MP/MP RangeN/A
Flash PointN/A
FlammabilityN/A
Autoignition TempN/A
Oxidizing PropertiesN/A
Explosive PropertiesN/A
Explosion LimitsN/A
Vapor PressureN/A
Partition CoefficientN/A
ViscosityN/A
Vapor DensityN/A
Saturated Vapor Conc.N/A
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Evaporation RateN/A
Bulk DensityN/A
Decomposition Temp.N/A
Solvent ContentN/A
Water ContentN/A
Surface TensionN/A
ConductivityN/A
Miscellaneous DataN/A
SolubilityN/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: UY0750000
ACUTE TOXICITY
LD50
Intravenous
Mouse
320 MG/KG
ROUTE OF EXPOSURE
Multiple Routes: May cause irritation. May be harmful by
inhalation, ingestion, or skin absorption.
CONDITIONS AGGRAVATED BY EXPOSURE
The toxicological properties have not been thoroughly
investigated.
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
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IATA
Non-hazardous for air transport.
15 - Regulatory Information
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
Self-Classification
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2010 Co. License granted to make
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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SECTION 16 - ADDITIONAL INFORMATION
N/A