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10H-Pyrido[3,2-b][1,4]benzothiazine-10-propanamine,N,N-dimethyl-, hydrochloride (1:1)

10H-Pyrido[3,2-b][1,4]benzothiazine-10-propanamine,N,N-dimethyl-, hydrochloride (1:1)


  • 中文别名:异THIPENDYL
  • 中文释义:异THIPENDYL
  • 英文别名:N,N-dimethyl-3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-1-amine,hydrochloride;
    (3-Benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-dimethyl-amin,Monohydrochlorid;
    Dominal hydrochloride;
    Dominal forte;
    (dimethyl)(10H-pyrido[3,2-b][1,4]benzothiazine-10-propyl)ammonium chloride;
    N,N-dimethyl-10H-pyrido[3,2-b][1,4]benzothiazine-10-propanamine,monohydrochloride;
    10-(3-Dimethylaminopropyl)-1-azaphenothiazine hydrochloride;
    Tolnate;
    Prothipendyl HCl;
    (3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-dimethyl-amine,monohydrochloride;
    Prothipendyl hydrochloride;
    Azacon 
  • CAS No.:1225-65-6
  • 分子式:

    C16H19N3S.ClH

  • 分子量:321.90
  • 精确分子量:321.10700
  • PSA:41.43000
  • InChI:The Key: CQJSAKJMCVSEGU-UHFFFAOYSA-N
  • 分子结构式:

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU8750000
CHEMICAL NAME :
10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(3-(dimethylamino)propyl)-, monohydrochloride
CAS REGISTRY NUMBER :
1225-65-6
LAST UPDATED :
199012
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C16-H19-N3-S.Cl-H
MOLECULAR WEIGHT :
321.90
WISWESSER LINE NOTATION :
T C666 BN DN ISJ B1Y1&N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
610 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
115 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1323 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
110 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972

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