2-Pyrazinamine,N-nitroso-
- 中文别名：亮氨酰亮氨酰亮氨酸
- 中文释义：Pyrazineamine, N-nitroso-, sodium salt
- 英文别名：Pyrazineamine, N-nitroso-, sodium salt;
pyrazin-2-yl-diazenol;
pyrazine-2-diazohydroxide;
Pyrazinyl-(2)-diazohydroxid
- CAS No.：103829-56-7
- 分子式：C4H4N4O
- 分子量：0
- 精确分子量：147.02800
- PSA：70.73000
- InChI：The Key: AUWFXUHWMBMPTI-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.47g/cm3
- 沸点：
- 227.1ºC at 760mmHg
- 闪点：
- 91.1ºC
- 折射率：
- 1.67
- 蒸汽压：
- 0.0791mmHg at 25°C
安全信息
- 密度：
- 1.47g/cm3
- 沸点：
- 227.1ºC at 760mmHg
- 闪点：
- 91.1ºC
- 折射率：
- 1.67
- 蒸汽压：
- 0.0791mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ2010000
- CHEMICAL NAME :
- Pyrazinamine, N-nitroso-
- CAS REGISTRY NUMBER :
- 103829-56-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C4-H4-N4-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 176 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - hair
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB88-239900
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Blood - leukopenia Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 29,511,1988 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg/5D-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death Related to Chronic Data - changes in testicular weight
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB88-239900
