2,3-Dioxabicyclo[3.3.1]nonan-7-one,4-[(1Z)-2-[2,4-bis(trifluoromethyl)phenyl]ethenyl]-4,8-dimethyl-,(1S,4R,5R,8S)-
- 中文别名：阿替夫林
- 中文释义：阿替夫林
- 英文别名：(1R,2R,5S,6S)-2-[(Z)-2-[2,4-bis(trifluoromethyl)phenyl]ethenyl]-2,6-dimethyl-3,4-dioxabicyclo[3.3.1]nonan-7-one;
Arteflene (USAN/INN);
Ro 42-1611;
UNII-5PE5HV9NF0;
2,3-Dioxabicyclo(3.3.1)nonan-7-one,4-(2-(2,4-bis(trifluoromethyl)phenyl)ethenyl)-4,8-dimethyl-(1S-(1alpha,4beta(Z),5alpha,8beta));
C19H18F6O3;
Arteflene
- CAS No.：123407-36-3
- 分子式：C19H18F6O3
- 分子量：0
- 精确分子量：408.11600
- PSA：35.53000
- 分子结构式：
物化性质
- 密度：
- 1.348g/cm3
- 沸点：
- 366.7ºC at 760mmHg
- 闪点：
- 169.6ºC
- 折射率：
- 1.507
- 蒸汽压：
- 1.43E-05mmHg at 25°C
安全信息
- 密度：
- 1.348g/cm3
- 沸点：
- 366.7ºC at 760mmHg
- 闪点：
- 169.6ºC
- 折射率：
- 1.507
- 蒸汽压：
- 1.43E-05mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JG6813000
- CHEMICAL NAME :
- 2,3-Dioxabicyclo(3.3.1)nonan-7-one, 4-(2-(2,4-bis(trifluoromethyl)phenyl)ethenyl)-4,8- dimethyl-, (1S-(1-alpha,4-beta(Z),5-alpha,8-beta))-
- CAS REGISTRY NUMBER :
- 123407-36-3
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H18-F6-O3
- MOLECULAR WEIGHT :
- 408.37
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- TMPRAD Tropenmedizin und Parasitologie. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.25- 1974- Volume(issue)/page/year: 45,261,1994
