1,3-Dioxolo[4,5-g]quinoline-7-carboxylicacid, 5,8-dihydro-5-methoxy-8-oxo-
- 中文别名：米洛沙星
- 中文释义：米洛沙星
- 英文别名：5-methoxy-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid;
AB 206;
Antibiotic AB 206;
Miloxacin
- CAS No.：37065-29-5
- 分子式：
C12H9NO6
- 分子量：263.22
- 精确分子量：263.04300
- PSA：86.99000
- InChI：The Key: ABQYZRZVRIPTPI-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.64g/cm3
- 沸点：
- 460.9ºC at 760mmHg
- 折射率：
- 1.689
安全信息
- 密度：
- 1.64g/cm3
- 沸点：
- 460.9ºC at 760mmHg
- 折射率：
- 1.689
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JI5060000
- CHEMICAL NAME :
- 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-5-methoxy-8-oxo-
- CAS REGISTRY NUMBER :
- 37065-29-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H9-N-O6
- MOLECULAR WEIGHT :
- 263.22
- WISWESSER LINE NOTATION :
- T C566 DO FO JN MV EHJ JO1 LVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 36400 mg/kg/26W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in uterine weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 413 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1650 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - parturition
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3300 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8100 mg/kg
- SEX/DURATION :
- female 17-22 day(s) after conception lactating female 21 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - physical
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 140 ug/L
- REFERENCE :
- AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 17,763,1980
海关数据
中国海关编码：2934999090
- 概述：
- 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
