10H-Phenothiazine-10-propanamine,N,N,b-trimethyl-2-(methylthio)-,hydrochloride (1:1)
- 中文别名：N,N,beta-三甲基-2-(甲硫基)-10H-吩噻嗪-10-丙胺单盐酸盐
- 中文释义：N,N,2-trimethyl-3-(2-methylsulfanylphenothiazin-10-yl)propan-1-amine,hydrochloride
- 英文别名：N,N,2-trimethyl-3-(2-methylsulfanylphenothiazin-10-yl)propan-1-amine,hydrochloride;
Promethazine sulfoxide;
10-(2-dimethyl-aminopropyl)-phenothiazine sulphoxide;
dimethyl-[2-methyl-3-(2-methylsulfanyl-phenothiazin-10-yl)-propyl]-amine,monohydrochloride;
Methiomeprazin*HCl;
Romergan sulfoxide;
Promethazine 5-Oxide;
10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide;
Promethiazine sulfoxide;
Promethazine 5-Sulfoxide;
promethasine sulfoxide;
methiomeprazine,monohydrochloride
- CAS No.：14056-64-5
- 分子式：
C19H24N2S2.ClH
- 分子量：381.03
- 精确分子量：380.11500
- PSA：57.08000
- InChI：The Key: KYBREXTVOMDAQC-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 沸点：
- 480.8ºC at 760 mmHg
- 闪点：
- 244.6ºC
- 蒸汽压：
- 2.1E-09mmHg at 25°C
安全信息
- 沸点：
- 480.8ºC at 760 mmHg
- 闪点：
- 244.6ºC
- 蒸汽压：
- 2.1E-09mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO6300000
- CHEMICAL NAME :
- Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-(methylthio)- , hydrochloride
- CAS REGISTRY NUMBER :
- 14056-64-5
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C19-H24-N2-S2.Cl-H
- MOLECULAR WEIGHT :
- 381.03
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B1Y1&1N1&1 ES1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 145 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972
