3H-Pyrido[3,4-b]indol-7-ol,4,9-dihydro-1-methyl-, hydrochloride (1:1)
- 中文别名：盐酸骆驼蓬酚
- 中文释义：盐酸骆驼蓬酚;3,4-二氢-1-甲基-9H-吡啶并(3,4-B)吲哚-7-醇;骆驼蓬酚 盐酸盐
- 英文别名：HARMALOL HCL;
harmalol dihydrochloride;
HARMALOL HYDROCHLORIDE
- CAS No.：6028-07-5
- 分子式：C12H12N2O.ClH
- 分子量：236.72
- 精确分子量：236.07200
- PSA：48.38000
- InChI：The Key: BSWAWVOHMZNXOS-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 熔点：
- 265-268ºC (dec.)
- 沸点：
- 507.5ºC at 760 mmHg
- 闪点：
- 231ºC
安全信息
- 熔点：
- 265-268ºC (dec.)
- 沸点：
- 507.5ºC at 760 mmHg
- 闪点：
- 231ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV1047000
- CHEMICAL NAME :
- 3H-Pyrido(3,4-b)indol-7-ol, 4,9-dihydro-1-methyl-, monohydrochloride
- CAS REGISTRY NUMBER :
- 6028-07-5
- LAST UPDATED :
- 198608
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C12-H12-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 236.72
- WISWESSER LINE NOTATION :
- T656 BM EN DUT&&J D1 LQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 3,218,1930
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 3,218,1930
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03207
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Cardiac - pulse rate Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 3,218,1930
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 3,218,1930
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 3,218,1930
海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
