4H-3,1-Benzoxazin-2-amine,6-chloro-N-ethyl-4-methyl-4-phenyl-
- 中文别名：艾替伏辛
- 中文释义：艾替伏辛;2-乙基氨基-6-氯-4-甲基-4-苯基-4H-3,1-苯并恶嗪
- 英文别名：6-chloro-N-ethyl-4-methyl-4-phenyl-3,1-benzoxazin-2-amine;
Etifoxinum [Latin];
(6-chloro-4-methyl-4-phenyl-4H-benzo[d][1,3]oxazin-2-yl)-ethyl-amine;
Etifoxine;
rac-etifoxine;
Etifoxina [Spanish];
Etifoxina [INN-Spanish];
Etifoxinum [INN-Latin];
Etifoxin;
Etafenoxine
- CAS No.：21715-46-8
- 分子式：C17H17ClN2O
- 分子量：300.81
- 精确分子量：300.10300
- PSA：33.62000
- InChI：The Key: IBYCYJFUEJQSMK-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.2g/cm3
- 熔点：
- 90-92℃
- 沸点：
- 421.2ºC at 760mmHg
- 闪点：
- 208.5ºC
- 折射率：
- 1.601
- 蒸汽压：
- 2.66E-07mmHg at 25°C
- 存储条件/存储方法：
- 库房低温,通风,干燥
安全信息
- 密度：
- 1.2g/cm3
- 熔点：
- 90-92℃
- 沸点：
- 421.2ºC at 760mmHg
- 闪点：
- 208.5ºC
- 折射率：
- 1.601
- 蒸汽压：
- 2.66E-07mmHg at 25°C
- 存储条件/存储方法：
- 库房低温,通风,干燥
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DM3028000
- CHEMICAL NAME :
- 4H-3,1-Benzoxazine, 6-chloro-2-ethylamino-4-methyl-4-phenyl-
- CAS REGISTRY NUMBER :
- 21715-46-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C17-H17-Cl-N2-O
- MOLECULAR WEIGHT :
- 300.81
- WISWESSER LINE NOTATION :
- T66 BN DO EHJ CM2 E1 ER& HG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,325,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 292 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,325,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,325,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1388 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,325,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,325,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 120 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,325,1972
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 133 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,325,1972
海关数据
中国海关编码：2934999090
- 概述：
- 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
