2,10,12,16,18-Nonadecapentaenoicacid,19-[(2S,3S)-3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-,(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-
- 中文别名：来普霉素B
- 中文释义：来普霉素B;来普霉素;细霉素B
- 英文别名：leptomycin B;
antibioticcl1957a;
2,10,12,16,18-nonadecapentaenoic acid;
antibioticci940;
7,9,11,15-hexamethyl-8-oxo--yl)-17-ethyl-6-hydroxy-5;
LEPTOMYCIN B FROM STREPTOMYCES SP;
Leptomycin B,(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoicacid
- CAS No.：87081-35-4
- 分子式：C33H48O6
- 分子量：540.7
- 精确分子量：540.34500
- PSA：100.90000
- InChI：The Key: YACHGFWEQXFSBS-XYERBDPFSA-N
- 分子结构式：
物化性质
- 外观与性状：
- 白色结晶固体
- 密度：
- 1.072 g/cm3
- 熔点：
- 41-44ºC
- 沸点：
- 725.8ºC at 760 mmHg
- 闪点：
- 224.7ºC
- 折射率：
- 1.542
安全信息
- 外观与性状：
- 白色结晶固体
- 密度：
- 1.072 g/cm3
- 熔点：
- 41-44ºC
- 沸点：
- 725.8ºC at 760 mmHg
- 闪点：
- 224.7ºC
- 折射率：
- 1.542
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RA5390000
- CHEMICAL NAME :
- 2,10,12,16,18-Nonadecapentanoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethy l- 6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-
- CAS REGISTRY NUMBER :
- 87081-35-4
- LAST UPDATED :
- 199412
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C33-H48-O6
- MOLECULAR WEIGHT :
- 540.81
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 1 umol/L
- REFERENCE :
- PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 26,253,1985
海关数据
中国海关编码：2916190090
- 概述：
- 2916190090 其他不饱和无环一元羧酸（包括其酸酐、酰卤化物，过氧化物和过氧酸以及它们的衍生物）。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装
- 监管条件：
- A.入境货物通关单B.出境货物通关单
- 检验检疫：
- R.进口食品卫生监督检验S.出口食品卫生监督检验M.进口商品检验N.出口商品检验
- 摘要/Summary：
- 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%
