2,10,12,16,18-Nonadecapentaenoicacid,19-[(2S,3S)-3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-,(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-
- 中文别名：来普霉素A
- 中文释义：来普霉素A
- 英文别名：leptomycin A;
(2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid;
2,10,12,16,18-Nonadecapentaenoic acid,19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo;
C32H46O6;
2,10,12,16,18-Nonadecapentaenoic acid,19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo;
Leptomycin A;
Jildamycin
- CAS No.：87081-36-5
- 分子式：C32H46O6
- 分子量：0
- 精确分子量：526.32900
- PSA：100.90000
- 分子结构式：
物化性质
- 密度：
- 1.079g/cm3
- 沸点：
- 717.7ºC at 760 mmHg
- 闪点：
- 224.2ºC
- 折射率：
- 1.544
安全信息
- 密度：
- 1.079g/cm3
- 沸点：
- 717.7ºC at 760 mmHg
- 闪点：
- 224.2ºC
- 折射率：
- 1.544
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RA5391000
- CHEMICAL NAME :
- 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)- 3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-
- CAS REGISTRY NUMBER :
- 87081-36-5
- LAST UPDATED :
- 199401
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C32-H46-O6
- MOLECULAR WEIGHT :
- 526.78
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Yeast - Schizosaccharomyces pombe
- DOSE/DURATION :
- 10 ug/L
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 38,1573,1985
