2-Propenoic acid,3-[6-(methylthio)-4-oxo-3(4H)-quinazolinyl]-, (2E)-
- 中文别名：硫克司特
- 中文释义：硫克司特
- 英文别名：(E)-3-(6-methylsulfanyl-4-oxoquinazolin-3-yl)prop-2-enoic acid;
TIACRILAST;
Ro-22-3747
- CAS No.：78299-53-3
- 分子式：C12H10N2O3S
- 分子量：0
- 精确分子量：262.04100
- PSA：97.49000
- InChI：The Key: VHFPVEGFRVEDBK-SNAWJCMRSA-N
- 分子结构式：
物化性质
- 密度：
- 1.38g/cm3
- 沸点：
- 499.3ºC at 760 mmHg
- 闪点：
- 255.8ºC
- 折射率：
- 1.658
安全信息
- 密度：
- 1.38g/cm3
- 沸点：
- 499.3ºC at 760 mmHg
- 闪点：
- 255.8ºC
- 折射率：
- 1.658
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UD3550000
- CHEMICAL NAME :
- 2-Propenoic acid, 3-(6-(methylthio)-4-oxo-3(4H)-quinazolinyl)-, (E)-
- CAS REGISTRY NUMBER :
- 78299-53-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H10-N2-O3-S
- MOLECULAR WEIGHT :
- 262.30
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,131,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,131,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,131,1985
海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
